The least used letters on ArXiv (source: <gwern.net/Variables>)
Pro tip: the best use of \Xi is for complex variables, that way you can get expressions like $\frac{\Xi}{\overline{\Xi}}$.

Jun 4, 2021 · 5:06 PM UTC

Also, oops-ilon
Starting a new trend: using υ to denote the error term. The letter's badly neglected, *and* its pronounced "oops-ilon".